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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AR 244555
Molecular formula	C23H23ClF2N2O
IUPAC name	(1'-but-3-enyl-5-chlorospiro[2H-indole-3,4'-piperidine]-1-yl)-(2,6-difluorophenyl)methanone
Molecular weight	416.897
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	(1'-but-3-enyl-5-chlorospiro[2H-indole-3,4'-piperidine]-1-yl)-(2,6-difluorophenyl)methanone NCGC00386715-01 AR-244555 GTPL7042 SCHEMBL5578980 AR244555 MolPort-042-665-829 ZINC169620334 D0Z2FF [ Show all ]
Inchi Key	QKPSTNGNDWHYCH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23ClF2N2O/c1-2-3-11-27-12-9-23(10-13-27)15-28(20-8-7-16(24)14-17(20)23)22(29)21-18(25)5-4-6-19(21)26/h2,4-8,14H,1,3,9-13,15H2
PubChem CID	59004159
ChEMBL	N/A
IUPHAR	7042
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554667	Proto-oncogene Mas	P04201	MAS1	Homo sapiens (Human)	325
554668	Proto-oncogene Mas	P12526	Mas1	Rattus norvegicus (Rat)	324

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