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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474473
Molecular formula	C29H29ClN6O3
IUPAC name	N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-(6-methoxypyridin-3-yl)benzamide
Molecular weight	545.04
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50412989 SCHEMBL1161850
Inchi Key	QIRVZVCPNDJFQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29ClN6O3/c1-19-23(18-36-29(38)27(30)25(17-33-36)35-14-12-31-13-15-35)4-3-5-24(19)34-28(37)21-8-6-20(7-9-21)22-10-11-26(39-2)32-16-22/h3-11,16-17,31H,12-15,18H2,1-2H3,(H,34,37)
PubChem CID	25209356
ChEMBL	CHEMBL474473
IUPHAR	N/A
BindingDB	50412989
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
279296	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
279295	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
279297	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
279294	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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