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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL84107
Molecular formula	C18H19N5O2
IUPAC name	N-(3-nitropyridin-2-yl)-3-[[(2R)-pyrrolidin-2-yl]methyl]-1H-indol-5-amine
Molecular weight	337.383
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.6
Synonyms	(R)-5-(3-Nitropyrid-2-ylamino)-3-(pyrrolidin-2-ylmethyl)-1H-indole BDBM50039566 QGSFFVWTEIOHEG-CYBMUJFWSA-N 3-[[(R)-Pyrrolidin-2-yl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine (3-Nitro-pyridin-2-yl)-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-amine SCHEMBL7841516 [ Show all ]
Inchi Key	QGSFFVWTEIOHEG-CYBMUJFWSA-N
Inchi ID	InChI=1S/C18H19N5O2/c24-23(25)17-4-2-8-20-18(17)22-14-5-6-16-15(10-14)12(11-21-16)9-13-3-1-7-19-13/h2,4-6,8,10-11,13,19,21H,1,3,7,9H2,(H,20,22)/t13-/m1/s1
PubChem CID	10427186
ChEMBL	CHEMBL84107
IUPHAR	N/A
BindingDB	50039566
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
277882	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
277883	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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