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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-J5PMS063XX
Molecular formula	C19H23ClN4O
IUPAC name	[5-chloro-6-[(6-methylpyridin-3-yl)amino]pyridin-3-yl]-[(2R)-2-ethylpiperidin-1-yl]methanone
Molecular weight	358.87
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.0
Synonyms	942510-68-1 J5PMS063XX CHEMBL593590 D0DX6U BDBM50305056 Methanone, (5-chloro-6-((6-methyl-3-pyridinyl)amino)-3-pyridinyl)((2R)-2-ethyl-1-piperidinyl)- (5-Chloro-6-((6-methylpyridin-3-yl)amino)pyridin-3-yl)-((2R)-2-ethylpiperidin-1-yl)methanone compound 16m ZINC45353419 GTPL6429 SCHEMBL990299 (R)-(5-chloro-6-(6-methylpyridin-3-ylamino)pyridin-3-yl)(2-ethylpiperidin-1-yl)methanone compound 16m [PMID: 19931453] [5-chloro-6-[(6-methylpyridin-3-yl)amino]pyridin-3-yl]-[(2R)-2-ethylpiperidin-1-yl]methanone [ Show all ]
Inchi Key	QABUURICQJOWID-MRXNPFEDSA-N
Inchi ID	InChI=1S/C19H23ClN4O/c1-3-16-6-4-5-9-24(16)19(25)14-10-17(20)18(22-11-14)23-15-8-7-13(2)21-12-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,22,23)/t16-/m1/s1
PubChem CID	23725699
ChEMBL	CHEMBL593590
IUPHAR	6429
BindingDB	50305056
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
273213	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
273212	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
273209	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
273211	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
273210	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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