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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3560612
Molecular formula	C23H22F2N2O4
IUPAC name	N-[4-[2-[1-[4-(difluoromethoxy)phenyl]-2,5-dimethylpyrrol-3-yl]-2-oxoethoxy]phenyl]acetamide
Molecular weight	428.436
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.6
Synonyms	VU0419799-1 AKOS001447854 MCULE-9070774728 ZINC12825407 MolPort-004-668-544
Inchi Key	OELJWSCTEOSSHN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22F2N2O4/c1-14-12-21(15(2)27(14)18-6-10-20(11-7-18)31-23(24)25)22(29)13-30-19-8-4-17(5-9-19)26-16(3)28/h4-12,23H,13H2,1-3H3,(H,26,28)
PubChem CID	16545124
ChEMBL	CHEMBL3560612
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
542333	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
492626	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
492625	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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