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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Molecular formula	C9H14ClN5
IUPAC name	4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Molecular weight	227.696
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.1
Synonyms	322691-38-3 BB 0259610 MCULE-7323487156 Oprea1_753606 4CH-019279 CHEMBL454007 W-7461 AKOS005173694 I03-1131 4-chloro-6-(4-methyl-1-piperazinyl)-2-pyrimidinamine Bionet2_000912 MolPort-008-154-112 SCHEMBL1024211 AC1LS9NN DTXSID60363305 ZINC1398295 2-Pyrimidinamine, 4-chloro-6-(4-methyl-1-piperazinyl)- ALBB-012297 KB-241571 NIQPQNNFLHVTLK-UHFFFAOYSA-N ST2405733 AJ-25629 FT-0684408 [ Show all ]
Inchi Key	NIQPQNNFLHVTLK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H14ClN5/c1-14-2-4-15(5-3-14)8-6-7(10)12-9(11)13-8/h6H,2-5H2,1H3,(H2,11,12,13)
PubChem CID	1484519
ChEMBL	CHEMBL454007
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
224249	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
224250	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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