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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-Acetyl-5-hydroxytryptamine
Molecular formula	C12H14N2O2
IUPAC name	N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide
Molecular weight	218.256
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	0.5
Synonyms	DB04275 SPECTRUM1500700 GTPL5451 TC-106303 KB-79213 L000433 MVAWJSIDNICKHF-UHFFFAOYSA-N N-Acetyl-5-hydroxytryptamine, >=99% (TLC), powder A 1824 N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide # Acetamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]- NCGC00015039-06 API0003477 NINDS_000668 CHEBI:17697 PDSP2_001634 PDSP2_001810 DTXSID00153106 Spectrum5_000975 HMS3372M05 UNII-P4TO3C82WV KBio2_003417 LP00044 N-ACETYL SEROTONIN 3-(2-Acetamidoethyl)-5-hydroxyindole N-Acetylserotonin; Normelatonin A804654 NCGC00015039-01 Acetyl-5-hydroxy-tryptamine NCGC00093558-02 BSPBio_003342 P4TO3C82WV CS-0030736 Serotonin,N-acetyl FT-0080684 SR-01000075660-1 I10-0829 ZINC66104 KBioGR_001856 MLS000859911 7506AH N-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-acetamide AC1Q1L68 NCGC00015039-04 AKOS004120085 NCGC00093558-05 CC-32273 PDSP1_001790 D0F9ZW Desmethylmelatonin Spectrum3_001871 HMS2235E22 Tox21_500044 KBio1_000668 Lopac-A-1824 N-(2-(5-hydroxy-1H-indol-3-yl)ethyl) acetamide 1210-83-9 N-acetyl-serotonin A-1300 N-[2-(5-hydroxyindol-3-yl)ethyl]acetamide Acetamide, N-[2-(5-hydroxyindol-3-yl)ethyl]- NCGC00015039-07 BDBM29612 Normelatonin PDSP2_001772 SCHEMBL422165 EINECS 214-916-5 Spectrum_000369 HMS502B10 VZ33043 KBio2_005985 MCULE-4114943625 N-acetyl serotonine 5-Hydroxy-N-acetyltryptamine N-Acetylserotonin\|\|\|Normelatonin AC1L1AAB NCGC00015039-02 acetylserotonin NCGC00093558-03 C-11937 PDSP1_001650 CTK8A9435 DB-007732 SMR000326772 FT-0629855 ST092857 IDI1_000668 KBioSS_000849 MolPort-001-736-385 N-Acetyl-5-hydroxytryptamine, 99% 7D6F82BE-C205-424F-9F26-65CE227610C0 N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide AC1Q5P6T NCGC00015039-05 ANW-17558 NCGC00260729-01 CCG-204140 PDSP1_001827 DivK1c_000668 Spectrum4_001268 HMS3260I09 Tryptamine, N-acetyl-5-hydroxy- KBio2_000849 Lopac0_000044 N-(2-(5-Hydroxy-1H-indol-3-yl)ethyl)acetamide N-acetylserotonin A1277 N-[2-(5-oxidanyl-1H-indol-3-yl)ethyl]ethanamide Acetamide,N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]- NCGC00093558-01 BRD-K26140483-001-01-3 O-Demethylmelatonin CHEMBL33103 PDSP2_001773 Serotonin, N-acetyl- EU-0100044 SR-01000075660 HY-107854 ZB002533 KBio3_002844 MFCD00005656 N-acetyl-5-HT 5-Hydroxymelatonin N-Acetyltryptamine,5-Hydroxy AC1Q1L67 NCGC00015039-03 ACMC-1BO7I NCGC00093558-04 C00978 PDSP1_001789 D00PDI [ Show all ]
Inchi Key	MVAWJSIDNICKHF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H14N2O2/c1-8(15)13-5-4-9-7-14-12-3-2-10(16)6-11(9)12/h2-3,6-7,14,16H,4-5H2,1H3,(H,13,15)
PubChem CID	903
ChEMBL	CHEMBL33103
IUPHAR	N/A
BindingDB	29612
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
214843	Melatonin receptor type 1A	O02781	MTNR1A	Sus scrofa (Pig)	154
214844	Melatonin receptor type 1A	P48039	MTNR1A	Homo sapiens (Human)	350
214842	Melatonin receptor type 1B	P49286	MTNR1B	Homo sapiens (Human)	362
214845	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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