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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL189089
Molecular formula	C22H30N4O2
IUPAC name	8-[butyl(ethyl)amino]-4-(4-methoxy-2-methylphenyl)-6-methyl-1,3-dihydropyrido[2,3-b]pyrazin-2-one
Molecular weight	382.508
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.3
Synonyms	8-[butyl(ethyl)amino]-4-(4-methoxy-2-methylphenyl)-6-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one BDBM20973 Pyridopyrazinone, 1a
Inchi Key	LYSNALHFMZZUFA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H30N4O2/c1-6-8-11-25(7-2)19-13-16(4)23-22-21(19)24-20(27)14-26(22)18-10-9-17(28-5)12-15(18)3/h9-10,12-13H,6-8,11,14H2,1-5H3,(H,24,27)
PubChem CID	11417694
ChEMBL	CHEMBL189089
IUPHAR	N/A
BindingDB	20973
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199663	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
487621	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
487620	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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