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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	6-CHLOROMELATONIN
Molecular formula	C13H15ClN2O2
IUPAC name	N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide
Molecular weight	266.725
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	2.2
Synonyms	HMS2234G13 LS-8570 N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide NCGC00015203-05 PDSP2_001769 Tox21_500178 Acetamide, N-(2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl)- CHEBI:109545 CTK8F7109 HMS3374G08 MLS002153444 N-[2-(6-CHLORO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE NCGC00024593-02 SMR001230810 6-Cl-melatonin BDBM50043289 EU-0100178 Lopac0_000178 N-Acetyl-6-chloro-5-methoxytryptamine NCGC00015203-03 NCGC00260863-01 SR-01000075735-3 AC1L1CE9 C 0331 HMS3260D17 LUINDDOUWHRIPW-UHFFFAOYSA-N N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide(6-Chloromelatonin) NCGC00015203-06 SCHEMBL677517 ZB002048 AKOS024458157 D0B8PD L000082 MolPort-004-964-764 NCGC00015203-01 NCGC00024593-03 SR-01000075735 6-Cl-MLT BRD-K34663752-001-02-6 GTPL1346 LP00178 N-[2-(5-Methoxy-6-chloroindol-3-yl)ethyl]acetamide NCGC00015203-04 PDSP1_001786 Tocris-0443 AC1Q3LDV CCG-204273 HMS3266A08 melatonin, 6-Chloro n-[2-(6-chloro-5-methoxy-1h-indol-3-yl)ethyl]acetamide NCGC00024593-01 SCHEMBL677518 ZINC57237 B6307 CHEMBL34730 DTXSID30213202 Lopac-C-0331 N-(2-(6-Chloro-5-methoxy-1H-indol-3-yl)ethyl)acetamide NCGC00015203-02 NCGC00024593-04 SR-01000075735-1 63762-74-3 BRN 0410191 [ Show all ]
Inchi Key	LUINDDOUWHRIPW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H15ClN2O2/c1-8(17)15-4-3-9-7-16-12-6-11(14)13(18-2)5-10(9)12/h5-7,16H,3-4H2,1-2H3,(H,15,17)
PubChem CID	1858
ChEMBL	CHEMBL34730
IUPHAR	1346
BindingDB	50043289
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
196614	Melatonin receptor type 1A	P48039	MTNR1A	Homo sapiens (Human)	350
196615	Melatonin receptor type 1A	P48040	MTNR1A	Ovis aries (Sheep)	366
196617	Melatonin receptor type 1A	O02781	MTNR1A	Sus scrofa (Pig)	154
196613	Melatonin receptor type 1B	P49286	MTNR1B	Homo sapiens (Human)	362
196616	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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