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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-O90RQ1XQ79
Molecular formula	C29H39N3O4
IUPAC name	N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Molecular weight	493.648
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.6
Synonyms	KGMOFBPANMLEMS-UHFFFAOYSA-N O90RQ1XQ79 E-2508 free base 685885-75-0 N-(Cyclopropylmethyl)-7-(2,6-dimethoxy-4-(methoxymethyl)phenyl)-2-ethyl-N-((tetrahydro-2H-pyran-4-yl)methyl)pyrazolo(1,5-a)pyridin-3-amine CHEMBL2087567 Pyrazolo(1,5-a)pyridin-3-amine, N-(cyclopropylmethyl)-7-(2,6-dimethoxy-4-(methoxymethyl)phenyl)-2-ethyl-N-((tetrahydro-2H-pyran-4-yl)methyl)- J2.971.745A BDBM50420920 N-cyclopropylmethyl-7-(2,6-dimethoxy-4-methoxymethylphenyl)-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]p yridin-3-amine E-2508 SCHEMBL3037677 [ Show all ]
Inchi Key	KGMOFBPANMLEMS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H39N3O4/c1-5-23-29(31(17-20-9-10-20)18-21-11-13-36-14-12-21)25-8-6-7-24(32(25)30-23)28-26(34-3)15-22(19-33-2)16-27(28)35-4/h6-8,15-16,20-21H,5,9-14,17-19H2,1-4H3
PubChem CID	10255153
ChEMBL	CHEMBL2087567
IUPHAR	N/A
BindingDB	50420920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
168623	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
460722	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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