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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3561788
Molecular formula	C20H21N3O2S2
IUPAC name	N-[4-[2-[2,5-dimethyl-1-(4-methyl-1,3-thiazol-2-yl)pyrrol-3-yl]-2-oxoethyl]sulfanylphenyl]acetamide
Molecular weight	399.527
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.0
Synonyms	MolPort-004-171-668 Z25065125 879334-38-0 N-[4-({2-[2,5-dimethyl-1-(4-methyl-1,3-thiazol-2-yl)-1H-pyrrol-3-yl]-2-oxoethyl}sulfanyl)phenyl]acetamide ZINC8429119 AKOS033931351 MCULE-3209674100 VU0419792-1 [ Show all ]
Inchi Key	JTDCETOEMIZIIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21N3O2S2/c1-12-10-27-20(21-12)23-13(2)9-18(14(23)3)19(25)11-26-17-7-5-16(6-8-17)22-15(4)24/h5-10H,11H2,1-4H3,(H,22,24)
PubChem CID	9535142
ChEMBL	CHEMBL3561788
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
540077	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
482582	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
482581	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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