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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-F35FTM8G49
Molecular formula	C25H33FN4O2
IUPAC name	4-fluoro-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexane-1-carboxamide
Molecular weight	440.563
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.7
Synonyms	CHEMBL38413 trans-4-Fluoro-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinylcyclohexanecarboxamide 4-fluoro-N-2-[4-(2-methoxyphenyl) piperazin-1-yl]ethyl-N-(2-pyridyl)cyclohexanecarboxamide Fcway BDBM50076428 SCHEMBL4636179 223699-45-4 Cyclohexanecarboxamide, 4-fluoro-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinyl-, trans- 4alpha-Fluoro-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexane-1alpha-carboxamide N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)-4-fluorocyclohexanecarboxamide SCHEMBL4636182 4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide F35FTM8G49 N-[2-[4-(2-Methoxyphenyl)piperazino]ethyl]-N-(2-pyridyl)-4alpha-fluoro-1beta-cyclohexanecarboxamide [ Show all ]
Inchi Key	JQSMVIQRTYWIED-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H33FN4O2/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20/h2-8,13,20-21H,9-12,14-19H2,1H3
PubChem CID	10048892
ChEMBL	CHEMBL38413
IUPHAR	N/A
BindingDB	50076428
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157600	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
157599	5-hydroxytryptamine receptor 1D	Q61224	Htr1d	Mus musculus (Mouse)	374

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