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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	NSC168466
Molecular formula	C17H15N3O
IUPAC name	2-[(E)-C-methyl-N-(quinolin-2-ylamino)carbonimidoyl]phenol
Molecular weight	277.327
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.0
Synonyms	(6Z)-6-[1-(2-quinolin-2-ylhydrazinyl)ethylidene]cyclohexa-2,4-dien-1-one AKOS000987288 NSC-168466 59034-56-9 CHEMBL1892026 SR-01000065365 AC1NY9IM MLS002702053 2-(1-(quinolin-2(1H)-ylidenehydrazono)ethyl)phenol CCG-38249 6-[1-(2-quinolin-2-ylhydrazinyl)ethylidene]cyclohexa-2,4-dien-1-one DTXSID20420923 SR-01000065365-1 AC1OBETT NCI168466 2-[(E)-C-methyl-N-(2-quinolylamino)carbonimidoyl]phenol SCHEMBL14075818 AC1NTLDI MLS-0463044.0001 ZINC84459882 [ Show all ]
Inchi Key	IZHPDVLGPQNUBP-XDHOZWIPSA-N
Inchi ID	InChI=1S/C17H15N3O/c1-12(14-7-3-5-9-16(14)21)19-20-17-11-10-13-6-2-4-8-15(13)18-17/h2-11,21H,1H3,(H,18,20)/b19-12+
PubChem CID	135443554
ChEMBL	CHEMBL1892026
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
561816	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
561815	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
561817	C-X-C chemokine receptor type 5	P32302	CXCR5	Homo sapiens (Human)	372

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