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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3342362
Molecular formula	C21H20F3N5O
IUPAC name	4-N-(cyclopropylmethyl)-6-pyridin-2-yl-2-N-[[4-(trifluoromethoxy)phenyl]methyl]pyrimidine-2,4-diamine
Molecular weight	415.42
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	4.9
Synonyms	BDBM50030770
Inchi Key	INMKYWPKBFAKSH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20F3N5O/c22-21(23,24)30-16-8-6-15(7-9-16)13-27-20-28-18(17-3-1-2-10-25-17)11-19(29-20)26-12-14-4-5-14/h1-3,6-11,14H,4-5,12-13H2,(H2,26,27,28,29)
PubChem CID	118716405
ChEMBL	CHEMBL3342362
IUPHAR	N/A
BindingDB	50030770
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
447100	G-protein coupled receptor 39	Q5U431	Gpr39	Mus musculus (Mouse)	456
447101	G-protein coupled receptor 39	O43194	GPR39	Homo sapiens (Human)	453

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