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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU0402477-1
Molecular formula	C18H19N3OS
IUPAC name	3-amino-4,6-dimethyl-N-[(4-methylphenyl)methyl]thieno[2,3-b]pyridine-2-carboxamide
Molecular weight	325.43
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.3
Synonyms	Oprea1_758238 ASN 02869379 ZINC420975 (3-amino-4,6-dimethylthiopheno[2,3-b]pyridin-2-yl)-N-[(4-methylphenyl)methyl]c arboxamide MCULE-9115979151 3-amino-4,6-dimethyl-N-[(4-methylphenyl)methyl]thieno[2,3-b]pyridine-2-carboxamide AC1LHK0S ST50310259 BDBM48051 3-amino-4,6-dimethyl-N-(4-methylbenzyl)thieno[2,3-b]pyridine-2-carboxamide Oprea1_756678 3-azanyl-4,6-dimethyl-N-[(4-methylphenyl)methyl]thieno[2,3-b]pyridine-2-carboxamide AKOS000726553 cid_864491 3-amino-4,6-dimethyl-N-[(4-methylphenyl)methyl]-2-thieno[2,3-b]pyridinecarboxamide [ Show all ]
Inchi Key	HMWVMJQMUBSSRH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19N3OS/c1-10-4-6-13(7-5-10)9-20-17(22)16-15(19)14-11(2)8-12(3)21-18(14)23-16/h4-8H,9,19H2,1-3H3,(H,20,22)
PubChem CID	864491
ChEMBL	N/A
IUPHAR	N/A
BindingDB	48051
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
460297	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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