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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL565799
Molecular formula	C27H19Cl2FN2O3S2
IUPAC name	(E)-N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[5-fluoro-3-methyl-1-(naphthalen-2-ylmethyl)indol-7-yl]prop-2-enamide
Molecular weight	573.478
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	7.7
Synonyms	4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Fluoro-3-methyl-1-naphthalen-2-ylmethyl-1H-indol-7-yl)acryloyl]amide BDBM50303661
Inchi Key	HIZNWXUSWJBZEM-CMDGGOBGSA-N
Inchi ID	InChI=1S/C27H19Cl2FN2O3S2/c1-16-14-32(15-17-6-7-18-4-2-3-5-19(18)10-17)26-20(11-21(30)12-22(16)26)8-9-24(33)31-37(34,35)25-13-23(28)27(29)36-25/h2-14H,15H2,1H3,(H,31,33)/b9-8+
PubChem CID	44627515
ChEMBL	CHEMBL565799
IUPHAR	N/A
BindingDB	50303661
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
116184	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
116187	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
116186	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
116183	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
116188	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
116185	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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