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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3357574
Molecular formula	C20H11ClFN3O3
IUPAC name	N-[3-chloro-4-(4-fluoro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide
Molecular weight	395.774
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50031312 N-[3-Chloro-4-(4-fluoro-1,3-dioxo-1,3-dihydro-2H-isoindole-2-yl)phenyl]-2-pyridinecarboxamide SCHEMBL1975043
Inchi Key	HDLABPAQQVOWQC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H11ClFN3O3/c21-13-10-11(24-18(26)15-6-1-2-9-23-15)7-8-16(13)25-19(27)12-4-3-5-14(22)17(12)20(25)28/h1-10H,(H,24,26)
PubChem CID	45110133
ChEMBL	CHEMBL3357574
IUPHAR	N/A
BindingDB	50031312
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
446116	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
446117	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912

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