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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	NSC686349
Molecular formula	C16H12O9S5
IUPAC name	tetramethyl 3'-oxospiro[1,3-dithiole-2,7'-dithiolo[4,3-b]thiopyran]-4,5,5',6'-tetracarboxylate
Molecular weight	508.563
Hydrogen bond acceptor	14
Hydrogen bond donor	0
XlogP	2.1
Synonyms	3-Oxospiro[4-thia-3H-1,2-benzodithiol-7(4H),2'-[1,3]dithiol]-4',5,5',6-tetracarboxylic acid tetramethyl ester CTK8D0161 Spiro[1,7'(3'H)-[1,2]dithiolo[4,3-b]- thiopyran]-4,5,5',6'-tetracarboxylic acid, 3'-oxo-, tetramethyl ester BDBM80083 NCIMech_000774 tetramethyl 3'-oxo-3'h-spiro[1,3-dithiole-2,7'-[1,2]dithiolo[4,3-b]thiopyran]-4,5,5',6'-tetracarboxylate 3''-ketospiro[1,3-dithiole-2,7''-dithiolo[4,3-b]thiopyran]-4,5,5'',6''-tetracarboxylic acid tetramethyl ester CHEMBL1708074 SMR001565925 MLS002702363 tetramethyl 3''-oxidanylidenespiro[1,3-dithiole-2,7''-[1,2]dithiolo[4,3-b]thiopyran]-4,5,5'',6''-tetracarboxylate CCG-36148 NSC-686349 tetramethyl 3'-oxospiro[1,3-dithiole-2,7'-dithiolo[4,3-b]thiopyran]-4,5,5',6'-tetracarboxylate 3''-oxospiro[1,3-dithiole-2,7''-dithiolo[4,3-b]thiopyran]-4,5,5'',6''-tetracarboxylic acid tetramethyl ester cid_389753 Spiro[1,3-dithiole-2,7'(3'H)-[1,2]dithiolo[4,3-b]thiopyran]-4,5,5',6'-tetracarboxylic acid, 3'-oxo-, tetramethyl ester AC1L8YMG NCI60_031078 tetramethyl 3''-oxospiro[1,3-dithiole-2,7''-dithiolo[4,3-b]thiopyran]-4,5,5'',6''-tetracarboxylate [ Show all ]
Inchi Key	HAODYRSOCXZKBJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H12O9S5/c1-22-11(17)5-6(12(18)23-2)26-9-10(29-30-15(9)21)16(5)27-7(13(19)24-3)8(28-16)14(20)25-4/h1-4H3
PubChem CID	389753
ChEMBL	CHEMBL1708074
IUPHAR	N/A
BindingDB	80083
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
110015	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
110016	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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