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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL289410
Molecular formula	C31H46ClN5O5
IUPAC name	(2S)-2-[[(2R)-3-(2-chloro-1H-indol-3-yl)-2-[[2-[[(2S,6R)-2,6-dimethylpiperidine-1-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]hexanoic acid
Molecular weight	604.189
Hydrogen bond acceptor	5
Hydrogen bond donor	5
XlogP	6.2
Synonyms	BDBM50284771 (S)-2-((R)-3-(2-Chloro-1H-indol-3-yl)-2-{2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-hexanoic acid
Inchi Key	GWMBPTBOMGCAGT-XXEUSHBOSA-N
Inchi ID	InChI=1S/C31H46ClN5O5/c1-6-7-14-24(30(40)41)34-29(39)26(17-22-21-13-8-9-15-23(21)33-27(22)32)35-28(38)25(16-18(2)3)36-31(42)37-19(4)11-10-12-20(37)5/h8-9,13,15,18-20,24-26,33H,6-7,10-12,14,16-17H2,1-5H3,(H,34,39)(H,35,38)(H,36,42)(H,40,41)/t19-,20+,24-,25?,26+/m0/s1
PubChem CID	44283349
ChEMBL	CHEMBL289410
IUPHAR	N/A
BindingDB	50284771
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
107044	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
107043	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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