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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL439968
Molecular formula	C25H28N2O3
IUPAC name	2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]phenyl]benzoic acid
Molecular weight	404.51
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.5
Synonyms	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid BDBM50042234 SCHEMBL684147 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-1,1'-biphenyl-2-carboxylic acid
Inchi Key	GJBPPMVTBDRYFK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28N2O3/c1-2-3-10-22-26-25(15-6-7-16-25)24(30)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,28,29)
PubChem CID	10069786
ChEMBL	CHEMBL439968
IUPHAR	N/A
BindingDB	50042234
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
97769	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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