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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17334378
Molecular formula	C20H19FN4O2
IUPAC name	5-(4-fluorophenyl)-2-[(2-methoxyanilino)methyl]-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	366.396
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM191571 5-(4-fluorophenyl)-2-(((2-methoxyphenyl)amino)methyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one US9676782, 6
Inchi Key	FKPGHMOFUVDODQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19FN4O2/c1-27-19-5-3-2-4-17(19)22-13-15-12-18-20(26)24(10-11-25(18)23-15)16-8-6-14(21)7-9-16/h2-9,12,22H,10-11,13H2,1H3
PubChem CID	118575137
ChEMBL	N/A
IUPHAR	N/A
BindingDB	191571
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559798	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
559797	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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