Zhang Lab

National University of Singapore

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL186214
Molecular formula	C15H16FNO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-phenylmethoxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	309.293
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-1.9
Synonyms	BDBM50151446 (1R,2R,3R,5R,6R)-2-Amino-3-benzyloxy-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Inchi Key	FHUJXFRDZNFBOI-ZNLHFFCSSA-N
Inchi ID	InChI=1S/C15H16FNO5/c16-14(12(18)19)9-6-10(15(17,11(9)14)13(20)21)22-7-8-4-2-1-3-5-8/h1-5,9-11H,6-7,17H2,(H,18,19)(H,20,21)/t9-,10-,11+,14-,15+/m1/s1
PubChem CID	11347391
ChEMBL	CHEMBL186214
IUPHAR	N/A
BindingDB	50151446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78703	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559744	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
78702	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417