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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL358335
Molecular formula	C24H25ClN6O2
IUPAC name	2-butyl-6-chloro-4-methyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4H-pyrimidine-5-carboxylic acid
Molecular weight	464.954
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.0
Synonyms	2-Butyl-4-chloro-1,6-dihydro-1-[4-[2-(1H-tetrazol-5-yl)phenyl]benzyl]-6-methylpyrimidine-5-carboxylic acid BDBM50004154 SCHEMBL9126709 2-Butyl-4-chloro-6-methyl-1-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,6-dihydro-pyrimidine-5-carboxylic acid
Inchi Key	FFGOUCLZEVSODP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25ClN6O2/c1-3-4-9-20-26-22(25)21(24(32)33)15(2)31(20)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)23-27-29-30-28-23/h5-8,10-13,15H,3-4,9,14H2,1-2H3,(H,32,33)(H,27,28,29,30)
PubChem CID	10322229
ChEMBL	CHEMBL358335
IUPHAR	N/A
BindingDB	50004154
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77061	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
77060	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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