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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-A9T9WVAH03
Molecular formula	C27H26N2O4S
IUPAC name	4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]naphthalene-1-carboxylic acid
Molecular weight	474.575
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.8
Synonyms	SCHEMBL6639612 BDBM50282362 2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4-carboxy-1-naphthalenyl)methyl)-1H-imidazol-5-yl)methylene)-, (E)- SB-203220 a-((2-Butyl-1-((4-carboxynaphthyl)methyl)-1H-imidazole-5-yl)methylene)-2-thiophenepropanoic acid 4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-naphthalene-1-carboxylic acid SCHEMBL6637138 A9T9WVAH03 144143-97-5 CHEMBL97533 [ Show all ]
Inchi Key	FDCUUQDMGDDHFO-XMHGGMMESA-N
Inchi ID	InChI=1S/C27H26N2O4S/c1-2-3-10-25-28-16-20(14-19(26(30)31)15-21-7-6-13-34-21)29(25)17-18-11-12-24(27(32)33)23-9-5-4-8-22(18)23/h4-9,11-14,16H,2-3,10,15,17H2,1H3,(H,30,31)(H,32,33)/b19-14+
PubChem CID	9869504
ChEMBL	CHEMBL97533
IUPHAR	N/A
BindingDB	50282362
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
75475	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
75476	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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