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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL268558
Molecular formula	C22H21ClN4
IUPAC name	1-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]pyrazolo[5,1-a]isoquinoline
Molecular weight	376.888
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.4
Synonyms	1-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[5,1-a]isoquinoline 1-[[4-(4-Chlorophenyl)piperazine-1-yl]methyl]pyrazolo[5,1-a]isoquinoline BDBM50073802 4-(4-Chloro-phenyl)-1-pyrazolo[5,1-a]isoquinolin-1-ylmethyl-piperazin-1-ium
Inchi Key	DUEAFIKCLDPEGV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21ClN4/c23-19-5-7-20(8-6-19)26-13-11-25(12-14-26)16-18-15-24-27-10-9-17-3-1-2-4-21(17)22(18)27/h1-10,15H,11-14,16H2
PubChem CID	44263882
ChEMBL	CHEMBL268558
IUPHAR	N/A
BindingDB	50073802
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68931	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
68933	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
68934	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
68932	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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