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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000082525
Molecular formula	C15H17N3O4S
IUPAC name	ethyl 2-[5-[[2-(4-methylphenoxy)acetyl]amino]-1,3,4-thiadiazol-2-yl]acetate
Molecular weight	335.378
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.1
Synonyms	HMS2303E16 ZINC4296040 AKOS032391961 CHEMBL1347747 MolPort-000-777-219 2-[5-[[2-(4-methylphenoxy)-1-oxoethyl]amino]-1,3,4-thiadiazol-2-yl]acetic acid ethyl ester ethyl 2-[5-[[2-(4-methylphenoxy)acetyl]amino]-1,3,4-thiadiazol-2-yl]acetate SMR000046348 AC1LDDCH BDBM67571 MCULE-7437753426 cid_665231 MolPort-002-628-176 2-[5-[[2-(4-methylphenoxy)acetyl]amino]-1,3,4-thiadiazol-2-yl]acetic acid ethyl ester ethyl [(5Z)-5-{[(4-methylphenoxy)acetyl]imino}-4,5-dihydro-1,3,4-thiadiazol-2-yl]acetate STL053786 AKOS005706752 ethyl 2-[5-[2-(4-methylphenoxy)ethanoylamino]-1,3,4-thiadiazol-2-yl]ethanoate REGID_for_CID_665231 714949-25-4 [ Show all ]
Inchi Key	DOWXYMBQDLYTJW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17N3O4S/c1-3-21-14(20)8-13-17-18-15(23-13)16-12(19)9-22-11-6-4-10(2)5-7-11/h4-7H,3,8-9H2,1-2H3,(H,16,18,19)
PubChem CID	665231
ChEMBL	CHEMBL1347747
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65430	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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