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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BDBM196630
Molecular formula	C20H17ClF2N4O
IUPAC name	(7S)-2-[(3-chloro-2-fluoroanilino)methyl]-5-(4-fluorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	402.83
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.0
Synonyms	(s)-2-(((3-chlorophenyl)amino)methyl)-5-(4-fluorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one US9676782, 49
Inchi Key	DOGOFKUFACMXBH-LBPRGKRZSA-N
Inchi ID	InChI=1S/C20H17ClF2N4O/c1-12-11-26(15-7-5-13(22)6-8-15)20(28)18-9-14(25-27(12)18)10-24-17-4-2-3-16(21)19(17)23/h2-9,12,24H,10-11H2,1H3/t12-/m0/s1
PubChem CID	134814146
ChEMBL	N/A
IUPHAR	N/A
BindingDB	196630
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559297	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
559298	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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