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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000661102
Molecular formula	C22H19NO3
IUPAC name	3,3-bis(4-hydroxyphenyl)-1,5-dimethylindol-2-one
Molecular weight	345.398
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.8
Synonyms	3,3-bis(4-hydroxyphenyl)-1,5-dimethylindol-2-one HMS2662L07 AKOS000353796 3,3-bis(4-hydroxyphenyl)-1,5-dimethyl-indol-2-one CHEMBL1445966 STK509058 MCULE-6049602383 3,3-bis(4-hydroxyphenyl)-1,5-dimethyl-1,3-dihydro-2H-indol-2-one BDBM61531 MolPort-002-086-571 3,3-bis(4-hydroxyphenyl)-1,5-dimethyl-oxindole cid_2895915 ZINC4164765 AC1MFKQY MLS-0269116.0001 3,3-bis(4-hydroxyphenyl)-1,5-dimethyl-2-indolone SMR000298386 [ Show all ]
Inchi Key	DLEHJJPGKGNIMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H19NO3/c1-14-3-12-20-19(13-14)22(21(26)23(20)2,15-4-8-17(24)9-5-15)16-6-10-18(25)11-7-16/h3-13,24-25H,1-2H3
PubChem CID	2895915
ChEMBL	CHEMBL1445966
IUPHAR	N/A
BindingDB	61531
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62878	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
62875	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
62877	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
62876	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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