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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1278714
Molecular formula	C19H18FN5O3
IUPAC name	3-[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrazol-4-yl]-1-[(2-fluorophenyl)methyl]imidazolidine-2,4-dione
Molecular weight	383.383
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.6
Synonyms	CHEMBL3965292 US9247759, 10-21 BDBM211273 DHTBKZDXNSKLRT-UHFFFAOYSA-N 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(2-fluorobenzyl)imidazolidine-2,4-dione
Inchi Key	DHTBKZDXNSKLRT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18FN5O3/c1-12-16(13(2)28-22-12)10-24-9-15(7-21-24)25-18(26)11-23(19(25)27)8-14-5-3-4-6-17(14)20/h3-7,9H,8,10-11H2,1-2H3
PubChem CID	57422443
ChEMBL	CHEMBL3965292
IUPHAR	N/A
BindingDB	211273
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
519968	Taste receptor type 2 member 8	Q9NYW2	TAS2R8	Homo sapiens (Human)	309

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