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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL604467
Molecular formula	C21H22F3N3
IUPAC name	1-methyl-2-[[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methyl]benzimidazole
Molecular weight	373.423
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.4
Synonyms	1-methyl-2-((4-(2-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-benzo[d]imidazole BDBM50343307
Inchi Key	DGWBQMLESHGUBF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22F3N3/c1-26-19-9-5-4-8-18(19)25-20(26)14-27-12-10-15(11-13-27)16-6-2-3-7-17(16)21(22,23)24/h2-9,15H,10-14H2,1H3
PubChem CID	46225569
ChEMBL	CHEMBL604467
IUPHAR	N/A
BindingDB	50343307
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59676	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
59675	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
59674	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
59677	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872

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