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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL145564
Molecular formula	C27H31ClN6O2
IUPAC name	ethyl 2-butyl-6-chloro-4,4-dimethyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidine-5-carboxylate
Molecular weight	507.035
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	2-Butyl-6-chloro-1,4-dihydro-4,4-dimethyl-1-[4-[2-(1H-tetrazol-5-yl)phenyl]benzyl]pyrimidine-5-carboxylic acid ethyl ester BDBM50004155 2-Butyl-6-chloro-4,4-dimethyl-1-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester
Inchi Key	DGKMIANMJJJSJY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31ClN6O2/c1-5-7-12-22-29-27(3,4)23(26(35)36-6-2)24(28)34(22)17-18-13-15-19(16-14-18)20-10-8-9-11-21(20)25-30-32-33-31-25/h8-11,13-16H,5-7,12,17H2,1-4H3,(H,30,31,32,33)
PubChem CID	10006413
ChEMBL	CHEMBL145564
IUPHAR	N/A
BindingDB	50004155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59338	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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