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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL186252
Molecular formula	C23H31BrN4O
IUPAC name	4-(2-bromo-4-propan-2-ylphenyl)-8-[butyl(ethyl)amino]-6-methyl-1,3-dihydropyrido[2,3-b]pyrazin-2-one
Molecular weight	459.432
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50155967 4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amino)-6-methyl-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Inchi Key	DGJZQKKOYYDIGL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H31BrN4O/c1-6-8-11-27(7-2)20-12-16(5)25-23-22(20)26-21(29)14-28(23)19-10-9-17(15(3)4)13-18(19)24/h9-10,12-13,15H,6-8,11,14H2,1-5H3,(H,26,29)
PubChem CID	10027220
ChEMBL	CHEMBL186252
IUPHAR	N/A
BindingDB	50155967
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59322	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
470250	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
470249	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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