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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	HYODEOXYCHOLIC ACID
Molecular formula	C24H40O4
IUPAC name	(4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Molecular weight	392.58
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	4.9
Synonyms	Iodeoxycholic acid SCHEMBL207643 .alpha.-Hyodeoxycholic acid 3.alpha.,6.alpha.-Dihydroxycholanic acid 3\|A,6\|A-Dihydroxy-5\|A-cholan-24-oic acid 5beta-Cholan-24-oic acid, 3alpha,6alpha-dihydroxy- (8CI) AB0014249 BDBM50375596 Cholan-24-oic acid, 3,6-dihydroxy-, (3a,5b,6a)- Hyodeoxycholate MFCD00003681 W-104141 3,6-Dihydroxy-5.beta.-cholan-24-oic acid, (3.alpha.,6.alpha.)- 3alpha,6alpha-Dihydroxy-5beta-cholan-24-saeure 5-.beta.-Cholanic acid-3-.alpha.,6-.alpha.-diol 6alpha-Hydroxylithocholate AJ-47432 C15517 DB11789 Hyodeoxycholic acid, >=98% Hyodesoxycholsaeure NSC 60672 (4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 3.alpha.,6.alpha.-Dihydroxy-5.beta.-cholanic acid 3alpha,6alpha-Dihydroxycholanic acid 5.beta.-Cholan-24-oic acid, 3.alpha.,6.alpha.-dihydroxy- 7A33Y6EHYK alpha-Hyodeoxycholic acid CHEMBL272621 HDCA K489 SMP1_000164 003H681 3alpha,6alpha-Dihydroxy-5 beta-cholan-24-oic acid 4-10-00-01600 (Beilstein Handbook Reference) 6-.alpha.-Hydroxylithocholic acid AC1NR33U BRD-K44009692-001-02-3 Cholan-24-oic acid, 3,6-dihydroxy-, (3alpha,5beta,6alpha)- MolPort-016-633-329 ZINC3918159 3-.alpha.,6-.alpha.-Dihydroxy-5-.beta.-cholan-24-oic acid 3alpha,6alpha-Dihydroxy-5beta-cholanic acid 5-beta-Cholan-24-oic acid, 3-alpha,6-alpha-dihydroxy- 6\|A-Dihydroxy-5\|A-cholan-24-oic acid AK323621 CHEBI:52023 DGABKXLVXPYZII-SIBKNCMHSA-N HYODEOXYCHOLIC_ACID Hyodesoxycholsaure s2311 (R)-4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 3.alpha.,6.alpha.-Dihydroxy-5.beta.-cholanoic acid 3\|A 83-49-8 AS-14254 Cholan-24-oic acid, 3,6-dihydroxy-, (3.alpha.,5.beta.,6.alpha.)- HY-N0169 LMST04010024 UNII-7A33Y6EHYK 10421-49-5 (hydrochloride salt) 3alpha,6alpha-Dihydroxy-5beta-cholan-24-oic acid 5 beta-Cholan-24-oic acid-3alpha,6alpha-diol 6-alpha-Hydroxylithocholic acid AHRO-001 BRN 3218394 CS-0007886 Hyodeoxycholic acid (HDCA) NCGC00386169-01 (3alpha,5beta,6alpha)-3,6-Dihydroxycholan-24-oic acid 3-alpha,6-alpha-Dihydroxy-5-beta-cholan-24-oic acid 3alpha,6alpha-Dihydroxy-5beta-cholanoic acid 5-beta-Cholanic acid-3-alpha,6-alpha-diol 7-Deoxyhyocholic acid AKOS022168200 EINECS 201-483-2 Hyodesoxycholic acid [ Show all ]
Inchi Key	DGABKXLVXPYZII-SIBKNCMHSA-N
Inchi ID	InChI=1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1
PubChem CID	5283820
ChEMBL	CHEMBL272621
IUPHAR	N/A
BindingDB	50375596
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59059	G-protein coupled bile acid receptor 1	Q8TDU6	GPBAR1	Homo sapiens (Human)	330

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