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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL53149
Molecular formula	C26H24Cl2N2O
IUPAC name	(2E)-5,5-bis(3-chlorophenyl)-N-(4-pyridin-3-ylbutyl)penta-2,4-dienamide
Molecular weight	451.391
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	7.0
Synonyms	SCHEMBL10398584 (E)-5,5-bis(3-chlorophenyl)-N-[4-(3-pyridinyl)butyl]-2,4-pentadienamide SCHEMBL10398585 BDBM50018376 DFLJFWPHOWAYHJ-LHHJGKSTSA-N 5,5-Bis-(3-chloro-phenyl)-penta-2,4-dienoic acid (4-pyridin-3-yl-butyl)-amide [ Show all ]
Inchi Key	DFLJFWPHOWAYHJ-LHHJGKSTSA-N
Inchi ID	InChI=1S/C26H24Cl2N2O/c27-23-11-3-9-21(17-23)25(22-10-4-12-24(28)18-22)13-5-14-26(31)30-16-2-1-7-20-8-6-15-29-19-20/h3-6,8-15,17-19H,1-2,7,16H2,(H,30,31)/b14-5+
PubChem CID	14347340
ChEMBL	CHEMBL53149
IUPHAR	N/A
BindingDB	50018376
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58657	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
58658	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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