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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL68638
Molecular formula	C31H36N4O3S
IUPAC name	3-cyclopentyl-N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]phenyl]sulfonylpropanamide
Molecular weight	544.714
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.8
Synonyms	4''-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-biphenyl-2-sulfonic acid (3-cyclopentyl-propionyl)-amide BDBM50282274
Inchi Key	DDHDEBQSQARBLD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H36N4O3S/c1-4-28-33-30-21(2)19-22(3)32-31(30)35(28)20-24-13-16-25(17-14-24)26-11-7-8-12-27(26)39(37,38)34-29(36)18-15-23-9-5-6-10-23/h7-8,11-14,16-17,19,23H,4-6,9-10,15,18,20H2,1-3H3,(H,34,36)
PubChem CID	44309719
ChEMBL	CHEMBL68638
IUPHAR	N/A
BindingDB	50282274
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57082	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
57083	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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