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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3714897
Molecular formula	C27H25N5O4
IUPAC name	2-(oxolan-2-ylmethoxy)-9-[(6-pyrimidin-5-ylpyridin-2-yl)methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
Molecular weight	483.528
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.3
Synonyms	9-(6-pyrimidin-5-yl-pyridin-2-ylmethoxy)-2-(tetrahydro-furan-2-ylmethoxy)-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one DCSIDQKAMACXGI-UHFFFAOYSA-N SCHEMBL15823197
Inchi Key	DCSIDQKAMACXGI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25N5O4/c33-27-31-26(36-16-22-4-2-10-34-22)12-25-23-7-6-21(11-18(23)8-9-32(25)27)35-15-20-3-1-5-24(30-20)19-13-28-17-29-14-19/h1,3,5-7,11-14,17,22H,2,4,8-10,15-16H2
PubChem CID	76684668
ChEMBL	CHEMBL3714897
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
523184	G-protein coupled receptor 84	Q9NQS5	GPR84	Homo sapiens (Human)	396

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