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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL326454
Molecular formula	C21H26ClN3O2
IUPAC name	N-[(3R,4R)-1-benzyl-4-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
Molecular weight	387.908
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.9
Synonyms	N-[(3R)-1-Benzyl-4alpha-methyl-3alpha-pyrrolidinyl]-2-methoxy-4-(methylamino)-5-chlorobenzamide BDBM50132696 N-((3R,4R)-1-Benzyl-4-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide
Inchi Key	DCJWAUUNGWWIFD-KUHUBIRLSA-N
Inchi ID	InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1
PubChem CID	9977532
ChEMBL	CHEMBL326454
IUPHAR	N/A
BindingDB	50132696
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
56419	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
56416	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
56418	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
56417	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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