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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17334418
Molecular formula	C21H21ClN4O2
IUPAC name	5-(2-chlorophenyl)-2-[(4-methoxy-N-methylanilino)methyl]-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	396.875
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.5
Synonyms	US9676782, 100 BDBM197333 5-(2-chlorophenyl)-2-(((4-methoxyphenyl)(methyl)amino)methyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one
Inchi Key	CZLOOFOZFGTQIK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21ClN4O2/c1-24(16-7-9-17(28-2)10-8-16)14-15-13-20-21(27)25(11-12-26(20)23-15)19-6-4-3-5-18(19)22/h3-10,13H,11-12,14H2,1-2H3
PubChem CID	118575178
ChEMBL	N/A
IUPHAR	N/A
BindingDB	197333
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558956	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
558957	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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