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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AMD 3465
Molecular formula	C24H38N6
IUPAC name	N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine
Molecular weight	410.61
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	0.8
Synonyms	HY-15971A UNII-IMD9Z48ZTT AMD3465 BDBM50270276 N-(2-pyridylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine AKOS030526677 CS-2786 Pyridin-2-ylmethyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmethyl)-benzyl]-amine 185991-24-6 AMD-3465 AMD3465 (Hexahydrobromide) IMD9Z48ZTT ZINC19361903 AC1LA8MA N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine 1-(pyridin-2-yl)-n-[4-(1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)benzyl]methanamine FT-0689764 SCHEMBL13527941 2-Pyridinemethanamine, N-((4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl)methyl)- AMD-3465 (Hexahydrobromide) AMD3465 hexahydrobromide MolPort-044-561-123 AC1Q4X3R CHEMBL477121 N-[1,4,8,11-Tetraazacyclotetradecanyl-1,4-phenylenebis(methylene)]-2-(amino-methyl)pyridine 185991-07-5 AMD 3465 (Hexahydrobromide) [ Show all ]
Inchi Key	CWJJHESJXJQCJA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2
PubChem CID	483559
ChEMBL	CHEMBL477121
IUPHAR	N/A
BindingDB	50270276
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52140	C-X-C chemokine receptor type 4	P61073	CXCR4	Homo sapiens (Human)	352

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