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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-Hydroxypropranolol
Molecular formula	C16H21NO3
IUPAC name	4-[2-hydroxy-3-(propan-2-ylamino)propoxy]naphthalen-1-ol
Molecular weight	275.348
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.6
Synonyms	14133-90-5 (hydrochloride) 4-[2-hydroxy-3-(isopropylamino)propoxy]naphthalen-1-ol 4-HYDROXY PROPRANOLOL AC1L3MBY CWEPACWBWIOYID-UHFFFAOYSA-N 1-(4-Hydroxynaphth-1-yloxy)-3-isopropylamino-2-propanol 4-[2-Hydroxy-3-(isopropylamino)propoxy]-1-naphthol AN-36817 4'-hydroxypropanolol 4-[2-hydroxy-3-(propan-2-ylamino)propoxy]naphthalen-1-ol CHEMBL1137 AC1Q7AX5 10476-53-6 4-[2-Hydroxy-3-(isopropylamino)propoxy]-1-naphthol # BDBM50405147 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)-1-naphthalenol CTK8D5320 4-HYDROXYPROPRANOLOL SULFATE AKOS030547981 [ Show all ]
Inchi Key	CWEPACWBWIOYID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21NO3/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16/h3-8,11-12,17-19H,9-10H2,1-2H3
PubChem CID	91565
ChEMBL	CHEMBL1137
IUPHAR	N/A
BindingDB	50405147
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52035	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
52034	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415

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