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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BUSERELIN
Molecular formula	C60H86N16O13
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular weight	1239.45
Hydrogen bond acceptor	15
Hydrogen bond donor	15
XlogP	-0.1
Synonyms	AC1Q5OOQ Buserelina [INN-Spanish] EINECS 261-061-9 KS-00002WUO O890 Suprefact (TN) 104428-01-5 57982-77-1 Buserelinum D-Ser(Tbu)6EA10LHRH GTPL3860 Luteinizing hormone-releasing hormone, (D-ser(tbu)(sup 6)-EA(sup 10))- PXW8U3YXDV W-105422 (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)-1-pyrrolidinyl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hy A831694 Buserelin [INN:BAN] CCRIS 2657 D07259 HS-2005 MolPort-009-194-174 SCHEMBL19409318 (D-Ser(tbu)(sup 6)-EA(sup 10))-LHRH AKOS015994645 Busereline CHEMBL2110824 Etilamide Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide- pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt acetate salt Tiloryth (TN) 111520-35-5 68630-75-1 (acetate salt) Buserelin (INN) Buserelinum [INN-Latin] D-Ser-(TBu)(sup 6)-LHRH-ethylamide HOE 766 Metrelef S 746766 (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-[bis(azanyl)methylideneamino]-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxi AC1L18ON Buserelina CHEBI:135907 des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide acetate salt ICI 123215 NCGC00181295-01 SCHEMBL19459955 (D-Ser(tbu)(sup 6)-EA(sup 10))-luteinizing hormone-releasing hormone AKOS030213242 Busereline [INN-French] D-Ser(tbu(sup 6))-LH-RH-(1-9)-nonapeptide ethylamide FT-0623289 Luteinizing hormone-releasing hormone (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide- Profact UNII-PXW8U3YXDV 982B771 Buserelin acetate salt C60H86N16O13 D04GSY HOE 766A MFCD00941414 SCHEMBL13354 (D-Ser(Bu(sup t)(sup 6)))-LH-RH(1-9)nonapeptide-ethylamide [ Show all ]
Inchi Key	CUWODFFVMXJOKD-UVLQAERKSA-N
Inchi ID	InChI=1S/C60H86N16O13/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65)/t40-,41-,42-,43-,44-,45-,46-,47+,48-/m0/s1
PubChem CID	50225
ChEMBL	CHEMBL2110824
IUPHAR	3860
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
517583	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
553492	Gonadotropin-releasing hormone receptor	Q01776	Gnrhr	Mus musculus (Mouse)	327

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