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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU0359480
Molecular formula	C22H18F2N4O2S
IUPAC name	3-amino-N-[(2,5-difluorophenyl)methyl]-4-methyl-6-(pyridin-2-ylmethoxy)thieno[2,3-b]pyridine-2-carboxamide
Molecular weight	440.469
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.5
Synonyms	3-amino-N-[(2,5-difluorophenyl)methyl]-4-methyl-6-(2-pyridinylmethoxy)-2-thieno[2,3-b]pyridinecarboxamide 3-amino-N-[(2,5-difluorophenyl)methyl]-4-methyl-6-(pyridin-2-ylmethoxy)thieno[2,3-b]pyridine-2-carboxamide BDBM48075 3-amino-N-(2,5-difluorobenzyl)-4-methyl-6-(2-pyridylmethoxy)thieno[2,3-b]pyridine-2-carboxamide 3-azanyl-N-[[2,5-bis(fluoranyl)phenyl]methyl]-4-methyl-6-(pyridin-2-ylmethoxy)thieno[2,3-b]pyridine-2-carboxamide cid_45142485 [ Show all ]
Inchi Key	CUKMKQWVAZBNDY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H18F2N4O2S/c1-12-8-17(30-11-15-4-2-3-7-26-15)28-22-18(12)19(25)20(31-22)21(29)27-10-13-9-14(23)5-6-16(13)24/h2-9H,10-11,25H2,1H3,(H,27,29)
PubChem CID	45142485
ChEMBL	N/A
IUPHAR	N/A
BindingDB	48075
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459678	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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