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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001116287
Molecular formula	C23H29ClN2O3
IUPAC name	2-(4-chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-piperidin-1-ylethyl]acetamide
Molecular weight	416.946
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.6
Synonyms	2-(4-chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-(1-piperidinyl)ethyl]acetamide STK909703 HMS2954M07 2-(4-chloranyl-3-methyl-phenoxy)-N-[2-(4-methoxyphenyl)-2-piperidin-1-yl-ethyl]ethanamide AKOS016167970 MolPort-000-486-339 2-(4-chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide CHEMBL1589201 Z27179673 880787-37-1 MCULE-2402832984 2-(4-chloro-3-methyl-phenoxy)-N-[2-(4-methoxyphenyl)-2-piperidino-ethyl]acetamide BDBM62151 SMR000625683 2-(4-chloro-3-methylphenoxy)-N-[2-(4-methoxyphenyl)-2-piperidin-1-ylethyl]acetamide cid_16438224 AKOS001519999 [ Show all ]
Inchi Key	CRAOTSUSWDADJO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29ClN2O3/c1-17-14-20(10-11-21(17)24)29-16-23(27)25-15-22(26-12-4-3-5-13-26)18-6-8-19(28-2)9-7-18/h6-11,14,22H,3-5,12-13,15-16H2,1-2H3,(H,25,27)
PubChem CID	16438224
ChEMBL	CHEMBL1589201
IUPHAR	N/A
BindingDB	62151
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48621	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
48619	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
48620	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328

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