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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3718451
Molecular formula	C27H27N5O4
IUPAC name	9-[[6-(1-methylpyrazol-4-yl)pyridin-2-yl]methoxy]-2-(oxolan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
Molecular weight	485.544
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.3
Synonyms	9-[6-(1-methyl-1H-pyrazol-4-yl)-pyridin-2-ylmethoxy]-2-(tetrahydro-furan-2-ylmethoxy)-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one CMUZGSPEHQURKQ-UHFFFAOYSA-N SCHEMBL15826584
Inchi Key	CMUZGSPEHQURKQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27N5O4/c1-31-15-19(14-28-31)24-6-2-4-20(29-24)16-35-21-7-8-23-18(12-21)9-10-32-25(23)13-26(30-27(32)33)36-17-22-5-3-11-34-22/h2,4,6-8,12-15,22H,3,5,9-11,16-17H2,1H3
PubChem CID	76684666
ChEMBL	CHEMBL3718451
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522853	G-protein coupled receptor 84	Q9NQS5	GPR84	Homo sapiens (Human)	396

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