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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	US8802673, 134
Molecular formula	C15H14F4N4O
IUPAC name	N-(2-fluoro-4-morpholin-2-ylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine
Molecular weight	342.298
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	2.1
Synonyms	CMBJWMKALAVUQV-UHFFFAOYSA-N (RS)-(2-Fluoro-4-morpholin-2-yl-phenyl)-(5-trifluoromethyl-pyrimidin-2-yl)-amine SCHEMBL12609771 US8802673, 135 CHEMBL3702019 US8802673, 121 BDBM129479 [ Show all ]
Inchi Key	CMBJWMKALAVUQV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H14F4N4O/c16-11-5-9(13-8-20-3-4-24-13)1-2-12(11)23-14-21-6-10(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)
PubChem CID	68325547
ChEMBL	CHEMBL3702019
IUPHAR	N/A
BindingDB	129479
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
45189	Trace amine-associated receptor 1	Q923Y8	Taar1	Mus musculus (Mouse)	332
45190	Trace amine-associated receptor 7b	Q923X8	Taar7b	Rattus norvegicus (Rat)	358

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