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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3401379
Molecular formula	C30H34F2N2O4
IUPAC name	N-[3,5-bis(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Molecular weight	524.609
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	6.8
Synonyms	BDBM50065607
Inchi Key	CLTJXNBVCMJRPD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H34F2N2O4/c1-3-21(4-2)20-30(36)13-15-34(16-14-30)29(35)33-24-17-27(37-25-9-5-22(31)6-10-25)19-28(18-24)38-26-11-7-23(32)8-12-26/h5-12,17-19,21,36H,3-4,13-16,20H2,1-2H3,(H,33,35)
PubChem CID	118728428
ChEMBL	CHEMBL3401379
IUPHAR	N/A
BindingDB	50065607
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443440	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
443441	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
443443	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
443442	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378

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