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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU0080241
Molecular formula	C19H23N5
IUPAC name	1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)pyrazolo[3,4-d]pyrimidine
Molecular weight	321.428
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.3
Synonyms	cid_3260619 MLS000419668 STL336201 AKOS021898571 F0518-0125 Oprea1_199133 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine MCULE-8819330672 SR-01000566242 393845-24-4 AC1MMGFZ D03MEI MolPort-000-728-354 BDBM50263670 GTPL6227 Oprea1_698469 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)pyrazolo[3,4-d]pyrimidine CHEMBL477396 MLS000100825 SR-01000566242-1 AKOS002088041 EU-0028524 NCGC00081401-02 BRD-A99482020-001-07-0 HMS2252F08 SMR000017000 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)pyrazolo[4,5-e]pyrimidine [ Show all ]
Inchi Key	CLQVVBPDAXJGBV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23N5/c1-13-6-7-17(15(3)9-13)24-19-16(10-22-24)18(20-12-21-19)23-8-4-5-14(2)11-23/h6-7,9-10,12,14H,4-5,8,11H2,1-3H3
PubChem CID	3260619
ChEMBL	CHEMBL477396
IUPHAR	6227
BindingDB	50263670
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44929	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
44930	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
44932	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
44928	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
44931	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
44927	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382

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