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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL37679
Molecular formula	C23H23ClN2O4S
IUPAC name	4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]-3-chlorobenzoic acid
Molecular weight	458.957
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.1
Synonyms	4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-3-chloro-benzoic acid SCHEMBL683415 BDBM50011975 (E)-3-[2-Butyl-1-(4-carboxy-2-chlorobenzyl)-1H-imidazol-5-yl]-2-(2-thienylmethyl)acrylic acid L004543 4-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-3-chloro-benzoic acid 1-[2-Chloro-4-carboxybenzyl]-2-butyl-alpha-[(2-thienyl)methyl]-1H-imidazole-5-propenoic acid SCHEMBL6642074 [ Show all ]
Inchi Key	CJLUYTOIWIIXFZ-LICLKQGHSA-N
Inchi ID	InChI=1S/C23H23ClN2O4S/c1-2-3-6-21-25-13-18(10-17(23(29)30)11-19-5-4-9-31-19)26(21)14-16-8-7-15(22(27)28)12-20(16)24/h4-5,7-10,12-13H,2-3,6,11,14H2,1H3,(H,27,28)(H,29,30)/b17-10+
PubChem CID	10321941
ChEMBL	CHEMBL37679
IUPHAR	N/A
BindingDB	50011975
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43476	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359
43477	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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