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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL76421
Molecular formula	C24H24N8O
IUPAC name	2,5-dimethyl-7-propyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-[1,2,4]triazolo[4,3-c]pyrimidin-3-one
Molecular weight	440.511
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.2
Synonyms	2,5-Dimethyl-7-propyl-8-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-[1,2,4]triazolo[4,3-c]pyrimidin-3-one BDBM50039361 LS-156794 2,5-Dimethyl-7-propyl-8-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-1,2,4-triazolo[4,3-c]pyrimidin-3(2H)-one
Inchi Key	CJCGCOGXWYIGGD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24N8O/c1-4-7-21-20(23-28-31(3)24(33)32(23)15(2)25-21)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)22-26-29-30-27-22/h5-6,8-13H,4,7,14H2,1-3H3,(H,26,27,29,30)
PubChem CID	10410991
ChEMBL	CHEMBL76421
IUPHAR	N/A
BindingDB	50039361
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43207	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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