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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3422433
Molecular formula	C41H46IN9O5
IUPAC name	(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-iodophenyl)propanoyl]amino]-N-[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight	871.781
Hydrogen bond acceptor	6
Hydrogen bond donor	8
XlogP	3.7
Synonyms	BDBM50080577
Inchi Key	CFEVUEANPOINQN-NZKHRDNMSA-N
Inchi ID	InChI=1S/C41H46IN9O5/c1-24(52)48-36(22-29-23-47-32-10-5-4-9-31(29)32)40(56)51-35(20-25-13-16-30(42)17-14-25)39(55)49-33(11-6-18-46-41(44)45)38(54)50-34(37(43)53)21-26-12-15-27-7-2-3-8-28(27)19-26/h2-5,7-10,12-17,19,23,33-36,47H,6,11,18,20-22H2,1H3,(H2,43,53)(H,48,52)(H,49,55)(H,50,54)(H,51,56)(H4,44,45,46)/t33-,34+,35+,36-/m0/s1
PubChem CID	118735610
ChEMBL	CHEMBL3422433
IUPHAR	N/A
BindingDB	50080577
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443294	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
443293	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
443296	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
443295	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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